Biology Department Faculty

Babak Momeni

Associate Professor

Department

Biology

Research

Communities of interacting microbes are abundant in nature and play critical roles at virtually all levels of life, ranging from global carbon cycling to the formation of oral cavities. Microbial communities can benefit us as resident microbiome, for example by facilitating food digestion or by blocking harmful pathogens. They can also harm us, for instance by causing persistent infections in slow-healing wounds or in lungs of cystic fibrosis patients.聽 Through interactions among species, microbial communities exhibit overall functions that cannot be achieved efficiently by any single member species. The aim of the lab is to understand how cell-level interactions among members lead to such community-level functions.

Complexity of natural microbial communities (involving many species, multitude of interactions, and non-steady environment) has impeded attempts to discover the link between community interactions and functions. To study microbial communities, our lab instead examines communities at different levels of complexity to search for general governing principles. These include simulated聽in silico聽communities, synthetic communities of microbes engineered to engage in defined interactions, and simple microbial communities isolated from nature. 聽Taking an interdisciplinary approach, we combine quantitative experimentation with mathematical modeling to discover interactions and to explain functions that arise from those interactions. Our long-term goal is to devise strategies to control microbial communities. This will have broad impact in biomedical applications (e.g. managing microbial infections), environmental applications (e.g. degrading waste), as well as industrial applications (e.g. producing biofuels).

Selected Publications

Biology

  • Zaccaria M, Dedrick S, Momeni B. . Processes. 2017 September 25; 5(4):53. doi:10.3390/pr5040053
  • Momeni B, Xie L, Shou W. . Elife. 2017 Mar 28;6. pii: e25051. doi:10.7554/eLife.25051.
  • Widder, S., R. Allen, T. Pfeiffer, T. Curtis, C. Wiuf, W. Sloan, O. Cordero, S. Brown, B. Momeni, W. Shou, H. Kettle, H. Flint, A. Haas, B. Laroche, J.-U. Kreft, P. Rainey, S. Freilich, S. Schuster, K. Milferstedt, J. Roelof Van der Meer, T. Grosskopf, J. Huisman, A. Free, C. Picioreanu, C. Quince, I. Klapper, S. Labarthe, B. Smets, H. Wang, Isaac Newton Institute Fellows, O. Soyer. 2016. 鈥.鈥 ISME J (March). doi:10.1038/ismej.2016.45.Kang, S., S. Kahan, and B. Momeni. 2014. 鈥.鈥 Methods in Molecular Biology (Clifton, N.J.) 1151: 233鈥53. doi:10.1007/978-1-4939-0554-6_16.
  • Momeni, B., A. Waite, and W. Shou. 2013. 鈥.鈥 eLife 2 (November): e00960. doi:10.7554/eLife.00960.
  • Momeni, B., K. Brileya, M. Fields, and W. Shou. 2013. 鈥.鈥 eLife, 2 (January): e00230. doi:10.7554/eLife.00230.
  • Momeni, B., and W. Shou. 2012. 鈥,鈥 Journal of Visual Experimentation, 70: e50101. doi:10.3791/50101.
  • Momeni, B., C. 鈥揅. Chen, K. Hillesland, A. Waite, and W. Shou. 2011. 鈥.鈥 Cellular and Molecular Life Sciences: CMLS 68 (8): 1353鈥68. doi:10.1007/s00018-011-0649-y.

Technology

  • Momeni, B., M. Askari, E. Shah Hosseini, A. Atabaki, and A. Adibi. 2010. 鈥.鈥 Journal of Optics 12 (3): 035501. doi:10.1088/2040-8978/12/3/035501.
  • Chamanzar, M., M. Soltani, B. Momeni, S. Yegnanarayanan, and A. Adibi. 2010. 鈥.鈥 Applied Physics B 101 (1-2): 263鈥71. doi:10.1007/s00340-010-4034-6.
  • Momeni, B., E. Shah Hosseini, M. Askari, M. Soltani, and A. Adibi. 2009. 鈥.鈥 Optics Communications 282 (15): 3168鈥71. doi:10.1016/j.optcom.2009.04.052.
  • Momeni, B., E. Shah Hosseini, and A. Adibi. 2009. 鈥.鈥 Optics Express 17 (19): 17060鈥69. doi:10.1364/OE.17.017060.
  • Momeni, B., S. Yegnanarayanan, M. Soltani, A. A. Eftekhar, E. Shah Hosseini, and A. Adibi. 2009. 鈥.鈥 Journal of Nanophotonics 3 (1): 031001鈥031001 鈥 23. doi:10.1117/1.3122986.
  • Momeni, B., M. Chamanzar, E. Shah Hosseini, M. Askari, M. Soltani, and A. Adibi. 2008. 鈥.鈥 Optics Express 16 (18): 14213鈥20. doi:10.1364/OE.16.014213.
  • Momeni, B., A. A. Eftekhar, and A. Adibi. 2007. 鈥.鈥 Optics Letters 32 (7): 778鈥80. doi:10.1364/OL.32.000778.
  • Tay, S., J. Thomas, B. Momeni, M. Askari, A. Adibi, P. J. Hotchkiss, S. C. Jones, S. R. Marder, R. A. Norwood, and N. Peyghambarian. 2007. 鈥.鈥 Applied Physics Letters 91 (22): 221109鈥221109 鈥 3. doi:10.1063/1.2817964.
  • Momeni, B., J. Huang, M. Soltani, M. Askari, S. Mohammadi, M. Rakhshandehroo, and A. Adibi. 2006. 鈥.鈥 Optics Express 14 (6): 2413鈥22. doi:10.1364/OE.14.002413.
  • Momeni, B., and A. Adibi. 2005. 鈥.鈥 Journal of Lightwave Technology 23 (3): 1522.
  • Momeni, B., and A. Adibi. 2005. 鈥溾 Applied Physics Letters 87 (17): 171104. doi:10.1063/1.2115081.
  • Momeni, B., and A. Adibi. 2003. 鈥.鈥 Applied Physics B: Lasers and Optics 77 (6-7): 555鈥60. doi:10.1007/s00340-003-1287-3.