Biology Department Faculty

David Burgess

Professor

Department

Biology

Research

*Dr. Burgess is no longer accepting trainees.

Our laboratory’s research is in a sub-area of cell biology. Specifically, we are interested in how cells change shape or form and how that is precisely regulated using the cytoskeleton. Molecular motors using cytoskeletal tracks are required for such intracellular movements as cytokinesis, endocytosis, exocytosis, axonal transport, and organellar movement in general. Although motors are required, many relatively basic questions are unanswered. Our laboratory is now focusing on the study of how microtubule asters translocate in cells and position such structures as sperm asters and mitotic spindles.Ìý Using micromanipulation, advanced imaging, reverse genetics, as well as biochemical approaches in dividing echinoderm and ascidian eggs, we are analyzing how the fertilizing sperm aster migrates in the egg after fertilization and subsequently captures the female pronuceus. We actively collaborate with other scientists around the world, including mathematical modelers, advanced imaging specialists, and experts at using eggs of marine animals.Ìý We share a laboratory with other scientists working on cell motility and cell division at the Marine Biological Laboratory during the summer months.Ìý

Selected Publications

  • Meaders JL, Burgess DR., Cells. 2020 Feb 23;9(2)PubMed PMID: 32102180; PubMed Central PMCID: PMC7072840.
  • Meaders, JL, de Matos SN, Burgess DR. 2020.Ìý A Pushing Mechanism for Cell Reports. Vol 33, https://doi.org/10.1016/j.celrep.2020.108213
  • Costache, V., Hebras, C., Pruliere, G., Besnardeau, L., Failla, M., Copley, R., Burgess, D., Chenevert, J., and McDougall, A. 2017. .ÌýNature Comm. 8, 917.
  • Bennett, M., J. Meaders, S. Ruvolo, D. Burgess. 2017. . In: Methods in Cell Biology: Cytokinesis.Ìý A. Echard, Ed.Ìý pp.Ìý 1-12.
  • Moorhouse, K., H, Gudejko,  A. McDougall, and D.R. Burgess. 2015.Ìý . Devel. Dynamics 244: 1469-1484.
  • Moorhouse, K. and D. Burgess. 2014.Ìý . Mol Reprod & Devel. 81: 884-895.
  • Andrew G. Campbell, Michael J. Leibowitz, Sandra A. Murray, David Burgess, Wilfred F. Denetclaw, Franklin A. Carrero-Martinez, and David J. Asai. 2013. . CBE Life Sci Educ 2013;12 394-402.
  • Gudekjo, H., Alford L., and Burgess, D.R. 2012. . Cytoskeleton 69:1000-1009.
  • Atilgan, E., Burgess, D.R., and Chang, F. 2012. . Cytoskeleton 69: 973-982.
  • Pollard, T.D., Burgess, D.R., and Mabuchi, I. 2012. . Cytoskeleton 69:659-679.
  • N. Minc, D. Burgess, and F. Chang.Ìý 2011.Ìý . Cell, 144: 414-426.Ìý
  • Alford, L. M., Ng, M. M., and Burgess, D. R. 2009. . Developmental Biology 330(1): 12–20.
  • Alford, L. M., and Burgess, D. R. 2008. 18(19): R921–3.
  • Burgess, D. R. 2008. . Biochemical Society Transactions 36: 384–386.
  • Burgess, D. R. 2007. Taking on that first °¬¿ÉÖ±²¥job. Nature 447: 1142.
  • Burgess, D. R. 2005. . Current Biology 15: R310–311.
  • Burgess, D. R., and Chang, F. 2005. . Trends in Cell Biology 15: 156–162.
  • Strickland, L. I., Donnelly, E. J., and Burgess, D. R. 2005. . Molecular Biology of the Cell 16: 4485–4494.
  • Ng, M., Chang, F., and Burgess, D.R. 2005. . Developmental Cell. 9: 781–90.
  • Strickland, L.I., Yen, Y., Gundersen, G.G., and Burgess, D. R. 2005. . Current Biology 15: 2249–2255.
  • Strickland, L. I., and Burgess, D. R. 2004. . Trends in Cell Biology 14: 115–118.
  • Strickland, L., Von Dassow, G., Ellenberg, J., Foe, V., Lenart, P., and Burgess, D. R. 2004. Light Microscopy of Echinoderm Embryos. In: The Development of Invertebrate Deuterostomes: Experimental Approaches. A Volume in Methods in Cell Biology. Edited by: Ettensohn, C.A., Wray, G., and Wessel, G. M.
  • Chang, F., and Burgess, D. 2003. . Current Biology 13: R692–R693.
  • Shuster, C. B., and Burgess, D. R. 2002. . Proceedings of the National Academy of Sciences of the USA 99: 3633–3638.
  • Shuster, C. B., and Burgess, D. R. 2002. . Current Biology 12 (10): 854–858.
  • Shuster, C. B., and Burgess, D. R. 1999. . Journal of Cell Biology 146: 981–992.
  • Stow, J. L., Fath, K. R., and Burgess, D. R. 1998. . Trends in Cell Biology 8: 138–141.
  • Fath, K., Trimbur, G., and Burgess, D. R. 1997. . Journal of Cell Biology 139: 1169–1181.
  • Ikonen, E., deAlmeid, J.B., Fath, K. R., Burgess, D., Ashman, K., Simons, K., and Stow, J. L. 1997. . Journal of Cell Science 110: 2155–2164.
  • Walker, G., Shuster, C. B., and Burgess, D. 1997. . Journal of Cell Science 110: 1373–1386.
  • Mamajiwalla, S. N., and Burgess, D. R. 1995. . Oncogene 11: 377–386.
  • Fath, K. R., Trimbur, G., and Burgess, D. R. 1994. . Journal of Cell Biology 126: 661–676.
  • Walker, G., Kane, R., and Burgess, D. R. 1994. . Journal of Cell Science 107: 2239–2248.
  • Fath, K. R., and Burgess, D. R. 1994. . Current Opinion in Cell Biology 6: 131–135.
  • Fath, K. R., and Burgess, D. R. 1993. . Journal of Cell Biology 120: 117–127.
  • Cartwright, C., Mamajiwalla, S., Eckhart, W., Skolnick, S. A., and Burgess, D. R. 1993. . Oncogene 8: 1033–1039.